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Ranked #1 in Longevity!
Shown to Reduce Biological Age by 8 Years
Rated from Over 4,500 Happy Customers
“I have taken vitamins for more than 30 years and never have I seen an improvement as big as Rejuvant”
“Increased energy levels, with noticeable improvements in appearance”
“More energy than coffee, this is making a difference”
Free Biological Age Test Kit with Subscription! Save $180
We stand behind Rejuvant and its amazing effects. So much that we offer a 120-day money back guarantee. If you don't feel better, we'll refund every penny. This means guaranteed results or your money back, no questions asked!
Research published in the December 2021 issue of the scientific journal ‘Aging’ showed that Rejuvant reduced biological age by an average of 8 years in just 7 months.
TruMe Labs' comprehensive DNA methylation test results have crowned Rejuvant as the top solution for longevity. With a stunning average reduction of 8 years in biological age, our controlled-released CaAKG supplement outshines the competition. Experience the leading edge in anti-aging science.
Ponce de Leon Health's Rejuvant is not just a supplement—it's a milestone in human longevity.
Rejuvant's exclusive controlled-released CaAKG formula delivers unparalleled results, significantly outperforming popular longevity supplements including NR and NAD+ boosters, resveratrol, spermidine, fisetin, and all other forms of Ca-AKG.
The leading supplement shown to significantly shown biological age. Our controlled-released CaAKG formula ensures optimal absorption and effectiveness, making Rejuvant the smart choice for those committed to living longer, healthier lives.
“The result was clear; the combination that became Rejuvant was by far the most effective at increasing healthspan and lowering biological age.”
“As an avid equestrian and athlete, focus and performance are absolutely crucial to me, which is why I can confidently say that Rejuvant is the one supplement I simply cannot live without.
Jacqueline K. | Verified Customer
Within just 10 days of incorporating, it into my routine, I experienced a remarkable transformation in my energy levels and concentration. Rejuvant has truly become an indispensable part of my daily life, and I love the way it makes me feel.”
Includes the addition of specific B vitamins which are cofactors in the demethylation process. With all ingredients blended into the controlled release mechanism, Rejuvant delivers the most powerful longevity ingredients all day long.
Rejuvant has been shown to reduce this age-related inflammation by blocking the excretion of inflammatory chemicals created by senescent cells.
Rejuvant encourages healthy aging by supplying more of the raw materials your body needs to repair your DNA and restore it to a more youthful state.
Rejuvant supercharges energy production in the cells so that you can move (and even think) faster than you have in years.
The AKG in Rejuvant extends life by activating this cell repair mode — without fasting — and your body invests more time in restoring your skin, joints, nerves, brain, and other vital organs so that they function at a much higher level.
Over time, toxic ammonia build up can cause permanent loss of brain power, muscle strength, and liver and kidney function. Rejuvant helps reduce this excess ammonia so that these organs become more efficient and work better.
Limited Time Offer: Save $180 Free Biological Age Test Kit with Subscription!
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“I am in great shape but had some digestive issues over recent years. Good friends turned me onto Rejuvant. Ok I'll try! I've been using it for three weeks now. No doubt about it, I've noticed a marked difference in my energy levels, workouts, and digestive system. I'm also waking up earlier with more energy.
Joe L. | Verified Customer
I've never accepted the age thing, and I just hit big 70 and will remain bold. Don't take that B off bold ever! No BS here I'm a believer in this product!”
Scientists at the Buck Institute for Research on Aging the global
leader in the field of anti-aging research tested Calcium
Alpha-Ketoglutarate, the key ingredient in Rejuvant, to investigate
its impact on slowing the aging process.
What they discovered was extraordinary.
Limited Time Offer: Save $180 Free Biological Age Test Kit with Subscription!
Buy Risk FreeHassle-Free Returns and Cancellations
Just two tablets of Rejuvant every morning is all it takes to build strength, increase endurance, feel more energetic, look younger, and live a healthier life.
But how?
The answer is Alpha-Ketoglutarate (AKG) — a substance essential for maintaining our youthful ability to repair cells, and our bodies naturally produce it. Production begins to decline around the age of 35-40, and by the time we reach 60, AKG levels can drop by a factor of 10. Unfortunately, AKG is found only in trace amounts in the food supply, making it impossible to get enough through diet alone. Supplementation is the only way to restore AKG levels in your cells.
AKG has very poor bioavailability, with a half-life of about 5 minutes. Within 30 minutes, it's completely out of your system. AKG is also highly acidic and can cause GI distress. This is where LifeAKG comes in. It includes a controlled-release mechanism that buffers against acidity and delivers CaAKG throughout the day, ensuring availability when needed.
Most manufacturing methods produce a CaAKG that's only 78% purity. We redeveloped and patented our manufacturing process, which yields a CaAKG over 98% pure. Rejuvant's patent-pending formula with highly bioavailable LifeAKG sets it apart from other products, providing consistent and effective results.
“I am 60 years old, but Rejuvant has lowered my biological age by over 8 years. Although I have never been athletic before, I now enjoy cycling and have completed two Metric Century rides (62 miles each) and am training for a 100-mile ride. I joined a cycling group and can even keep up with the boys.
Lisa M. - Virginia | Verified Customer
My mood has improved, I owe it all to Rejuvant!”
“What makes Rejuvant a MUST-use product for our programs and clinicians at the Human Longevity Institute is that this research-backed product can aid in turning back the biological aging clocks by 8 years in approximately 7 months regardless of lifestyle and other therapeutic interventions.”
Dr. Melissa Petersen, DC, MS, BCHH Founder Human Longevity Institute
We stand behind Rejuvant and its amazing effects. So much that we offer a 120-day money back guarantee. If you don't feel better, we'll refund every penny. This means guaranteed results or your money back, no questions asked!
Select Your Offer Below:
Retail Price: $149.95
$99 .95 once
You Save: $50
Retail Price: $259.95
$79 .95 /month
You Save: $180*
*The first Free Biological Age test kit is available right away and the second Free Biological Age kit after 7 months of receiving Rejuvant.
If you have any questions, you'll find the answers below
Take two tablets in the morning, with or without food. The controlled-release formula is designed to deliver active ingredients steadily throughout the day, so consistency matters more than timing. Just make it part of your daily routine.
Rejuvant works at the cellular level, so results build gradually. Many users notice improved energy, focus, and recovery within the first few weeks. In the first few months, increases in aerobic capacity and athletic performance are also commonly reported. The most significant change, a reduction in biological age, typically becomes measurable after about 6 to 7 months of consistent use.
There are no known negative interactions with common supplements. We've even tested Rejuvant alongside popular compounds like NMN and fisetin, and found no interference—though no added benefit to biological age, either. As always, if you're taking prescription medications or managing a health condition, it's best to consult your healthcare provider.
Most AKG supplements break down within minutes and are less than 78% pure. Rejuvant uses a patented manufacturing process to produce over 98% pure Ca-AKG, combined with a controlled-release delivery system that extends absorption over hours—not minutes. It's also the only AKG-based supplement shown in a published, peer-reviewed study to reduce biological age by an average of 8 years.
LifeAKG is our patented, high-purity form of calcium alpha-ketoglutarate (Ca-AKG), the active ingredient in Rejuvant. It is over 98% pure and delivered through a controlled-release system designed to maximize absorption in the small intestine. LifeAKG is the core component behind the biological age reduction seen in published human studies.
Rejuvant is the only longevity formula clinically shown to reduce biological age by an average of 8 years in an independent, peer-reviewed study. It uses a patented, high-purity Ca-AKG combined with targeted B vitamins and a controlled-release delivery system for maximum effect. Unlike many products built on theory or hype, Rejuvant is built on measurable results.
Our research showed that men and women respond differently to certain nutrient combinations. To stay true to the science, we formulated each version with the most effective ingredient blend for its respective group. The core ingredient, LifeAKG, remains the same—only the supporting vitamins differ based on what worked best in our testing.
The main ingredient AKG has been found to be safe in large quantities in published studies. We designed our product to be effective, however, some may benefit from more than 1 dose a day. If you have health concerns, please consult your physician.
Log in to your account and click on "Manage Subscriptions." From there, you can update your shipping address, change delivery frequency, skip a shipment, or cancel at any time.
On the login page, click "Forgot password?" and follow the instructions. You'll receive an email with a secure link to reset it.
After logging into your account, go to “Account Details” to update your shipping address or payment method.
Yes. Once your order ships, you'll receive a confirmation email with tracking information. You can also view tracking details anytime in your account under “Order History.”
You can cancel your subscription at any time by logging into your account and selecting “Manage Subscriptions.” Click “Cancel” next to the product you'd like to remove.
You can reach us directly at [email protected] or 1-844-735-8826, and we'll be happy to assist you.
The TruMe test uses a saliva sample to analyze DNA methylation at specific CpG sites—regions of your genome that reflect how your body is aging at a cellular level. That information is run through their algorithm to reveal your biological age rather than your chronological age.
No. The TruMe test is completely non-invasive—you collect your saliva at home, mail it in with prepaid shipping if you're in the U.S., and receive your full report within 3-4 weeks of sample receipt.
TruMe's test has a reported mean absolute deviation of about 3–4 years, meaning it provides a reliable biological age estimate. Accuracy is optimized when you follow collection instructions, stay hydrated, and avoid eating, drinking (except water), or brushing your teeth 30 minutes before sampling.
Yes. TruMe Labs operates in a CLIA-certified lab and adheres to validated protocols suitable for genetic research, though it is not a clinical diagnostic test.
Absolutely. Retesting every six months lets you see how your biological age is changing. Many Rejuvant users pair the test with supplementation to track cellular-level improvements.
TruMe offers a replacement kit if your sample is invalid or compromised during shipping. They'll also notify you if your sample fails to meet quality standards.
No, TruMe only looks at certain sites in your epigenome. No personally identifiable genetic information is taken or used.